Connecticut Children's Grand Rounds

5.2.23, Dr. Donna Zeiter Memorial Lecture, "Notch Signaling for All of Us: Development, Disease, Demise, and De-Cure!", David Piccoli, MD

Review the importance of Notch Signaling in Development and Specifically Human Development.
Review Alagille Syndrome and related disorders of human development and the genetic causes of these diseases.
Explain the role of Notch Signaling in other (non-developmental) human diseases.
Associate and hypothesize roles for modulation of Notch Signaling as therapy.