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Marriage and Sex in the Age of Ozempic: An Update

This week, The Daily is revisiting some of our favorite episodes of the year and checking in on what has happened in the time since. In the past few years, GLP-1 weight-loss drugs like Ozempic and Zepbound have been radically reshaping the people’s lives, changing appetites and health. But the drugs also have the power to affect other parts of consumers’ lives, including their romantic relationships. Lisa Miller, who writes about health for The New York Times, tells the story of how these drugs upended one couple’s marriage.
Duration
23m
Broadcast on
26 Dec 2025
Audio Format
other

This week, The Daily is revisiting some of our favorite episodes of the year and checking in on what has happened in the time since.

In the past few years, GLP-1 weight-loss drugs like Ozempic and Zepbound have been radically reshaping the people’s lives, changing appetites and health.

But the drugs also have the power to affect other parts of consumers’ lives, including their romantic relationships.

Lisa Miller, who writes about health for The New York Times, tells the story of how these drugs upended one couple’s marriage.

Guest: Lisa Miller, a domestic correspondent for the Well section who writes about personal and cultural approaches to physical and mental health.

Background reading: 

Photo: Katherine Wolkoff for The New York Times

For more information on today’s episode, visit nytimes.com/thedaily. Transcripts of each episode will be made available by the next workday. 

For more information on today’s episode, visit nytimes.com/thedaily. Transcripts of each episode will be made available by the next workday.

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This podcast is supported by TikTok. Sometimes the most interesting discoveries are the ones you weren't looking for. That happens every day on TikTok. A science experiment can spark a whole new interest. A recipe you stumble upon can become a meal you make for the people you love. And a restaurant you've never heard of might become your new favorite spot. That's the thing about TikTok. Follow your curiosity and see where it leads. Your next discovery is waiting on TikTok. Hey, it's Rachel. This week we're visiting some of our favorite shows from the year, listening back and hearing what's happened at the time since then. Today, we return to the story of one married couples experience with GLP1 drugs and how the use of weight loss medications like Ozempic can impact how people see themselves and their closest relationships. It's Friday, December 26th. Lisa, I don't think it's an understatement to say that we, in 2025 or in the middle of this, what feels like kind of a weight loss revolution in the United States. And of course, we're talking about these drugs that everybody's probably heard of. Ozempic, WeGoV, Monjaro. I think most people know somebody who's been transformed by them, maybe a lot of people themselves have actually had some experience with them. Yeah, it's a revolution in how we look. It's a revolution in our health. It's got gigantic potential to help people who have not been able to be helped before. The data show that one in eight Americans has tried one of these drugs. Like I have a friend who takes the medicine, and he says, you know, if you are able to eat just five french fries and you used to not be able to eat just five french fries, it gives you grounding in the idea that you can control things in your life, that you didn't think you could control. So what else can you control? Can you control the way you relate to your children, the way you talk to your boss? And what really interested me was this question of how the GLP1 drugs affected a marriage, especially when one partner is on the drugs and the other partner isn't.

Transcription truncated.

This week, The Daily is revisiting some of our favorite episodes of the year and checking in on what has happened in the time since. In the past few years, GLP-1 weight-loss drugs like Ozempic and Zepbound have been radically reshaping the people’s lives, changing appetites and health. But the drugs also have the power to affect other parts of consumers’ lives, including their romantic relationships. Lisa Miller, who writes about health for The New York Times, tells the story of how these drugs upended one couple’s marriage.