The Dylan Gemelli Podcast - Episode #161: What’s Making You Sick: Cholesterol, Mitochondria & Chronic Disease Featuring DR. WILL COLE!!

What if the reason you feel tired, inflamed, foggy or simply OFF actually begins at theCELLULAR LEVEL? Leading functional medicine expert Dr. Will Cole reveals why cellular dysfunction may be atthe root of chronic health problems, what modern life is doing to our cells and whyaddressing the root cause of disease requires looking far beyond symptoms and lab results. Dr. Will Cole is one of the leading voices in functional medicine and started one of the firstfunctional medicine telehealth centers in the world over a decade ago. Named one of the top50 functional and integrative doctors in the nation, he is the host of The Art Of Being Wellpodcast and the New York Times bestselling author of Intuitive Fasting, Ketotarian, TheInflammation Spectrum and Gut Feelings. His new book, Heal Your Cells, co-authored withDr. Josh Axe, explores how improving cellular health may help address chronic symptoms,support longevity and optimize the way your body functions. In this episode, he explains: ◼Why normal bloodwork doesn’t always mean optimal health◼Why chronic health problems may begin with dysfunction at the cellular level◼How your cell membrane affects hormones, mitochondria, energy and aging◼How food, meal timing, artificial light, toxins, stress and trauma can affect cellular health◼Why AI, technology and social isolation may be weakening our resilience and health◼How HRV reveals what may be happening with your nervous system◼Why cold plunges, fasting and other biohacks can become harmful when taken too far◼Why there may be no universally healthy food for every person◼The truth about creatine, electrolytes, melatonin, vitamin D, K2 and magnesium Chapters:(00:00) Intro(00:44) Just Thrive(02:09) Meet Dr. Will Cole(09:31) What Is Functional Medicine?(10:42) Why Normal Lab Results May Not Mean You’re Healthy(12:00) Finding the Root Cause of Chronic Health Problems (16:29) Do We Rely Too Much on Medication?(19:43) Functional Medicine vs. Traditional Doctor Visits(23:53) Are Doctors Taught Enough About Nutrition?(26:19) Community Is Medicine(29:01) AI, Loneliness & The Decline of Human Connection(37:07) What AI May Be Doing to Your Brain(40:33) Faith, Gratitude & Their Connection to Health(44:52) Social Media, Negativity & Mental Health(50:52) Heal Your Cells(52:33) Cell Membrane Matters More Than You Think(55:39) What Is Damaging Your Cells?(59:21) Cholesterol, LDL & Cellular Health(1:03:46) EMFs, Wearables & Wireless Technology(1:08:09) HRV & Nervous System Regulation(1:11:41) Are Cold Plunges Overrated?(1:14:54) Why Biohacking Must Be Personalized(1:18:08) The Problem With Extreme Diet Advice(1:18:50) Is Oatmeal Actually Bad for You?(1:22:17) Spinach, Oxalates & Food Fear-Mongering(1:25:37) Supplements: What’s Actually Worth Taking?(1:26:22) Creatine(1:27:42) Electrolytes(1:29:46) Melatonin(1:31:47) Vitamin D3 + K2(1:32:26) Magnesium(1:33:57) Final Thoughts GET Dr. Will Cole and Dr. Josh Axe's NEW BOOK HERE! https://www.penguinrandomhouse.com/books/812741/heal-your-cells-by-dr-josh-axe-and-dr-will-cole/ Follow Will Cole: Instagram: https://www.instagram.com/drwillcole/?hl=en The Art of Being Well:https://drwillcole.com/podcast/ https://www.youtube.com/user/drwillcole https://podcasts.apple.com/hr/podcast/the-art-of-being-well/id1539535133 https://open.spotify.com/show/6z1lJ5dfKNHwGGQPOFTc7E?si=f45fb0aedb284f57 https://art19.com/shows/the-art-of-being-well Books by Dr. Will Cole:https://drwillcole.com/books-home-page/ —--------------------------------------------------------------------------TODAYS EPISODE IS SPONSORED BY JUST THRIVE ProbioticsUse my link below and receive 90 DAYS OF FREE Digestive Bitters when you sign up for 90days of the Probiotic!!! https://justthrivehealth.com/DYLAN ALSO Take 20% off at Just Thrive SITE WIDE with my link below https://justthrivehealth.com/DYLANGEMELLI —--------------------------------------------------------------------------Get your FREE Mitopure Gu

Duration: 1h 35m
Broadcast on: 09 Sep 2026
Audio Format: other

What if the reason you feel tired, inflamed, foggy or simply OFF actually begins at the
CELLULAR LEVEL?

Leading functional medicine expert Dr. Will Cole reveals why cellular dysfunction may be at
the root of chronic health problems, what modern life is doing to our cells and why
addressing the root cause of disease requires looking far beyond symptoms and lab results.

Dr. Will Cole is one of the leading voices in functional medicine and started one of the first
functional medicine telehealth centers in the world over a decade ago. Named one of the top
50 functional and integrative doctors in the nation, he is the host of The Art Of Being Well
podcast and the New York Times bestselling author of Intuitive Fasting, Ketotarian, The
Inflammation Spectrum and Gut Feelings. His new book, Heal Your Cells, co-authored with
Dr. Josh Axe, explores how improving cellular health may help address chronic symptoms,
support longevity and optimize the way your body functions.

In this episode, he explains:

◼Why normal bloodwork doesn’t always mean optimal health
◼Why chronic health problems may begin with dysfunction at the cellular level
◼How your cell membrane affects hormones, mitochondria, energy and aging
◼How food, meal timing, artificial light, toxins, stress and trauma can affect cellular health
◼Why AI, technology and social isolation may be weakening our resilience and health
◼How HRV reveals what may be happening with your nervous system
◼Why cold plunges, fasting and other biohacks can become harmful when taken too far
◼Why there may be no universally healthy food for every person
◼The truth about creatine, electrolytes, melatonin, vitamin D, K2 and magnesium

Chapters:
(00:00) Intro
(00:44) Just Thrive
(02:09) Meet Dr. Will Cole
(09:31) What Is Functional Medicine?
(10:42) Why Normal Lab Results May Not Mean You’re Healthy
(12:00) Finding the Root Cause of Chronic Health Problems

(16:29) Do We Rely Too Much on Medication?
(19:43) Functional Medicine vs. Traditional Doctor Visits
(23:53) Are Doctors Taught Enough About Nutrition?
(26:19) Community Is Medicine
(29:01) AI, Loneliness & The Decline of Human Connection
(37:07) What AI May Be Doing to Your Brain
(40:33) Faith, Gratitude & Their Connection to Health
(44:52) Social Media, Negativity & Mental Health
(50:52) Heal Your Cells
(52:33) Cell Membrane Matters More Than You Think
(55:39) What Is Damaging Your Cells?
(59:21) Cholesterol, LDL & Cellular Health
(1:03:46) EMFs, Wearables & Wireless Technology
(1:08:09) HRV & Nervous System Regulation
(1:11:41) Are Cold Plunges Overrated?
(1:14:54) Why Biohacking Must Be Personalized
(1:18:08) The Problem With Extreme Diet Advice
(1:18:50) Is Oatmeal Actually Bad for You?
(1:22:17) Spinach, Oxalates & Food Fear-Mongering
(1:25:37) Supplements: What’s Actually Worth Taking?
(1:26:22) Creatine
(1:27:42) Electrolytes
(1:29:46) Melatonin
(1:31:47) Vitamin D3 + K2
(1:32:26) Magnesium
(1:33:57) Final Thoughts

GET Dr. Will Cole and Dr. Josh Axe's NEW BOOK HERE!

https://www.penguinrandomhouse.com/books/812741/heal-your-cells-by-dr-josh-axe-and-dr-will-cole/

Follow Will Cole:

Instagram: https://www.instagram.com/drwillcole/?hl=en

The Art of Being Well:
https://drwillcole.com/podcast/

https://www.youtube.com/user/drwillcole

https://podcasts.apple.com/hr/podcast/the-art-of-being-well/id1539535133

https://open.spotify.com/show/6z1lJ5dfKNHwGGQPOFTc7E?si=f45fb0aedb284f57

https://art19.com/shows/the-art-of-being-well

Books by Dr. Will Cole:
https://drwillcole.com/books-home-page/

—--------------------------------------------------------------------------
TODAYS EPISODE IS SPONSORED BY JUST THRIVE Probiotics
Use my link below and receive 90 DAYS OF FREE Digestive Bitters when you sign up for 90
days of the Probiotic!!!

https://justthrivehealth.com/DYLAN

ALSO Take 20% off at Just Thrive SITE WIDE with my link below

https://justthrivehealth.com/DYLANGEMELLI

—--------------------------------------------------------------------------
Get your FREE Mitopure Gummies Sample Here:

https://timeline.com/gemelli

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Get the Apollo Neuro for $99 OFF!! Use Code GEMELLI!

https://apolloneuro.com/gemelli

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TRULY Increase Your NAD LEVELS with WONDERFEEL NMN:

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Where to find Dylan

◼ Follow Dylan on Instagram - https://www.instagram.com/dylangemelli/

◼ Visit Dylan’s website - https://dylangemelli.com/

◼ The Dylan Gemelli Podcast Youtube Channel - https://www.youtube.com/@thedylangemellipodcast

◼ Spotify - https://open.spotify.com/show/3In4QlJj4IvHqq0eduKj7m

◼Apple Podcast - https://podcasts.apple.com/hr/podcast/the-dylan-gemelli-podcast/id1780873400

- But healthy people don't need pharmaceutical drugs. It's not a great business model to get people healthy for a certain industry. - Funny story here, maybe not so funny. In prison, I learned that ibuprofen was the answer to everything. - I think we all need to do it, especially in this age of AI. To be pro human is to get out there, to reach out to people, 'cause there's a loneliness epidemic. I think it was out of MIT, that found that people that use AI to write essays, which so many people do. It was associated with a 55% decrease use of the brain. Dr. Cole, are you indicating that crushing LDL is not optimal for cellular health? - I know, shocking. I would say that's one of the worst things you could do. It's probably easier to change someone's religion than the foods they eat. People come so ideologically tribal about it, they make it their personality. - Do you wanna know why nothing seems to help you with constant cravings? GLP1 is the hunger hormone that everyone's talking about, but your gut was designed to make it on its own, however it needs the right signal. Bitter receptors in your gut and mouth are directly tied to GLP1 release, and most modern diets are extremely low in bitter foods, and so this natural pathway rarely gets activated, but have no fear because I found the answer with just-drive-digested bitters. Just-drive-digested bitters deliver concentrated bitter botanicals that activate receptors in your gut, encouraging your body to produce GLP1 naturally, supporting healthy digestion, comfortable fullness, and a balanced appetite without any synthetic inputs. No bitter taste required. The bitter receptors that matter most for GLP1 signaling and digestive support aren't just in your mouth. They line your entire GI tract, so when the capsule dissolves in your gut, the bitter botanicals activate those receptors, same signal, same response, zero bitter taste. Right now, just-drive is offering my listeners something special. When you start a 90-day just-drive probiotic subscription, you'll get a free 90-day supply of their new digestive bitters,

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